General Cell Lines and Cell Cultures
Biochain Institute Inc Paraffin Tissue Section Panel - Human Tumor, Different Tumor Type, Different Donors, Panel V, 8 tissue spots, 5 slides/PK
BioChain's FFPE multiple tissue panels with different types of tumors are designed for screening gene expression in multiple tumor tissues. Each tumor tissue is paired with a corresponding normal control tissue. A licensed pathologist issued a pathological diagnosis of each tumor based on examination of tissue sections. Documentation of tissues' clinical histories is available upon request. mRNA Northern blot and Western blots as well as total RNA Norterhn blot are available in identical formats.
Eurofins Discoverx PathHunter U2OS EphA7 Functional Assay, 2 vials. (93-0841C3)
The PathHunter U2OS EphA7 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphA7 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphA7 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Amsbio LLC Lyophilized microvesicles from NCI-H1975 cell line
Lyophilized microvesicles from NCI-H1975 cell line
Biochain Institute Inc Frozen Tissue Section - Progressive Supranuclear Palsy: Brain: Pons, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Angio Proteomie Human Retinal Astrocytes, 1.0 Frozen Vial
HRAs (cAP-0115) are isolated from normal human retinal tissue. The cells are shipped in frozen vials (the cells are provided @ passage 2). Astrocyte Growth Medium (AsGM, contains FBS and Growth factor supplements, cAP-29) is recommended for cell culture and these cells have a minimum average population doubling levels > 10 when cultured following the detailed protocol described below).
Eurofins Discoverx PathHunter Human GPR55 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR55 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR55 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Amsbio LLC p53 Leeporter™ Luciferase Reporter-HeLa Cell Line
p53 Leeporter™ Luciferase Reporter-HeLa Cell Line
Eurofins Discoverx PathHunter CHO-K1 CALCR (No RAMP) β-Arrestin Cell Line, 2 vials. (93-0566C2)
The PathHunter CALCR (No RAMP) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. calcitonin) based activation of CALCR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CALCR and EA-tagged β-Arrestin-2. Activation of CALCR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx Ready-to-Assay GLP-1 Receptor Frozen Cells, 2 Vials of Cells. (HTS163LRTA)
The Ready-to-Assay GLP-1 Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. GLP-1) based activation of GLP1R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GLP1R alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of GLP1R, the resulting calcium activity can be assayed in either detection mode. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Genscript Corporation ICOS Fc Chimera Human
Inducible T-cell costimulator is an immune checkpoint protein that in humans is encoded by the ICOS gene CD278 or ICOS (Inducible T-cell COStimulator) is a CD28-superfamily costimulatory molecule that is expressed on activated T cells It is thought to be important for Th2 cells in particular The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family It forms homodimers and plays an important role in cell-cell signaling immune responses and regulation of cell proliferation
ATCC Pfizer Pneumococcal polysaccharide powder Type 70 (d33F) 10mg
Purified pneumococcal polysaccharide type 33F (US type 70) is manufactured by Pfizer, Inc., for small-quantity distribution by ATCC. The pneumococcal polysaccharide type 33F can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Eurofins Discoverx PathHunter U2OS mOPRM1 β-Arrestin Cell Line, 2 vials. (93-0524C3)
The PathHunter mOPRM1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. met 5-enkephalin) based activation of mOPRM1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mOPRM1 and EA-tagged β-Arrestin-2. Activation of mOPRM1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
American Research Products Inc PrEST Antigen CLK2
PrEST Antigen CLK2 antigen APrEST85735 for CDC-like kinase 2 Recombinant protein fragment of Human CLK2
Biochain Institute Inc Frozen Tissue Section - Arrhythmia, infarct: Heart, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
